Adolescent Violence Prevention: A Case Presentation

Violence in adolescence has seen an increase since the 1990s with dramatic statistics on violent death and risk behaviors. School violence has been focused upon by a huge media coverage of especially violent cases that could have had some endemic consequences worldwide. We present a case of a 14 year old white male with change in school behavior, strategies for the case investigation, its results, and long term prevention. Other research has shown that preventive measures during pregnancy, infancy and childhood can prevent adolescent and adult delinquency

The Ursinus Weekly, February 25, 1952

Frats begin rushing for new pledges • Sororities to start rushing March 3 • Any student urged to try out for Spring production • Freshman dance to be celestial • Group plays postponed • History of Anglo-Egyptian relations traced by speaker • Jeanne Careless chosen queen • Campaign against cutting campus begun by WSGA • Newman Club hears psychology talk • Blood donations sought again here • Piano-violin concert received favorably by Ursinus audience • Economics of marriage discussed at seminar • Fastnacht ball planned by clubs • Editorials: Needed - codified law; Is Korean War necessary? • Student Union ideas given • Five initiated into Rosicrucians society • Canterbury Club holds supper • Engagement • Forum tickets available • Former German student comes to Ursinus this semester • Dr. C. L. Chandler receives honor • Mr. Dolman gives Twain selections at English readings • Guest lecturer tells of history of aeronautics • Ursinus students glimpse preview of Mardi Gras scene • Grizzlies trounce Textile to break losing streak • Badminton squad defeats Rosemont in opening game • Beaver College basketball team deadlocks Snell\u27s Belles at 25 • Girls\u27 intramural loop is underway • Beaver hands Ursinus Mermaids first loss • Penn JVs overpower girls\u27 badminton team • Chess Club wins • Grizzlies defeated by Bucknell team • Ursinus quintet stifles Ford rally to win 71-51 • League I champs may be crowned in tonight\u27s play • Doctor speaks on psychiatry to studentshttps://digitalcommons.ursinus.edu/weekly/1535/thumbnail.jp

Effects of Nerve Growth Factor from the venom of Vipera russelli on sensory and sympathetic ganglia from the embryonic chick in culture

SUMMARY Sensory and sympathetic ganglia of embryonic chick were cultured in media in which no growth of fibres occurred, and then transferred to culture conditions favouring the growth of fibres. The effects on fibre outgrowth of having NGF in neither, one or both media were examined quantitatively. It was concluded that the main effect of NGF, under these conditions, is to maintain the viability of the neurons. Subsidiary experiments supporting this view are also reported

PCR and Omics Based Techniques to Study the Diversity, Ecology and Biology of Anaerobic Fungi:Insights, Challenges, and Opportunities

Anaerobic fungi (phylum Neocallimastigomycota) are common inhabitants of the digestive tract of mammalian herbivores, and in the rumen, can account for up to 20% of the microbial biomass. Anaerobic fungi play a primary role in the degradation of lignocellulosic plant material. They also have a syntrophic interaction with methanogenic archaea, which increases their fiber degradation activity. To date, nine anaerobic fungal genera have been described, with further novel taxonomic groupings known to exist based on culture-independent molecular surveys. However, the true extent of their diversity may be even more extensively underestimated as anaerobic fungi continue being discovered in yet unexplored gut and non-gut environments. Additionally many studies are now known to have used primers that provide incomplete coverage of the Neocallimastigomycota. For ecological studies the internal transcribed spacer 1 region (ITS1) has been the taxonomic marker of choice, but due to various limitations the large subunit rRNA (LSU) is now being increasingly used. How the continued expansion of our knowledge regarding anaerobic fungal diversity will impact on our understanding of their biology and ecological role remains unclear; particularly as it is becoming apparent that anaerobic fungi display niche differentiation. As a consequence, there is a need to move beyond the broad generalization of anaerobic fungi as fiber-degraders, and explore the fundamental differences that underpin their ability to exist in distinct ecological niches. Application of genomics, transcriptomics, proteomics and metabolomics to their study in pure/mixed cultures and environmental samples will be invaluable in this process. To date the genomes and transcriptomes of several characterized anaerobic fungal isolates have been successfully generated. In contrast, the application of proteomics and metabolomics to anaerobic fungal analysis is still in its infancy. A central problem for all analyses, however, is the limited functional annotation of anaerobic fungal sequence data. There is therefore an urgent need to expand information held within publicly available reference databases. Once this challenge is overcome, along with improved sample collection and extraction, the application of these techniques will be key in furthering our understanding of the ecological role and impact of anaerobic fungi in the wide range of environments they inhabit

Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site

Systemic tolerance can be elicited by introducing antigen into an immune-privileged site, such as the eye, or directly into the blood. Both routes of immunization result in a selective deficiency of systemic delayed type hypersensitivity. Although the experimental animal model of anterior chamber–associated immune deviation (ACAID) occurs in most mouse strains, ACAID cannot be induced in several mutant mouse strains that are coincidentally deficient in natural killer T (NKT) cells. Therefore, this model for immune-privileged site–mediated tolerance provided us with an excellent format for studying the role of NKT cells in the development of tolerance. The following data show that CD1-reactive NKT cells are required for the development of systemic tolerance induced via the eye as follows: (a) CD1 knockout mice were unable to develop ACAID unless they were reconstituted with NKT cells together with CD1+ antigen-presenting cells; (b) specific antibody depletion of NKT cells in vivo abrogated the development of ACAID; and (c) anti-CD1 monoclonal antibody treatment of wild-type mice prevented ACAID development. Significantly, CD1-reactive NKT cells were not required for intravenously induced systemic tolerance, thereby establishing that different mechanisms mediate development of tolerance to antigens inoculated by these routes. A critical role for NKT cells in the development of systemic tolerance associated with an immune-privileged site suggests a mechanism involving NKT cells in self-tolerance and their defects in autoimmunity